Representative articles since 2005
Oral Administration of (S)-Allyl-l-Cysteine and Aged Garlic Extract to Rats: Determination of Metabolites and Their Pharmacokinetics. Planta Med 2017, 83(17):1351-1360.
Circadian clock is involved in regulation of hepatobiliary transport mediated by multidrug resistance-associated protein 2. J Pharm Sci 2017, 106(9):2491-2498.
High-Dose Metformin May Increase the Concentration of Atorvastatin in the Liver by Inhibition of Multidrug Resistance-Associated Protein 2. J Pharm Sci 2017. 106(4), 961-967.
Pharmacokinetics of drugs in mutant Nagase analbuminemic rats and responses to select diuretics J Pharm Pharmacol 2014, 66 (1), 2-13.
Role of drug transporters: an overview based on knockout animal model studies. J Pharm Invest 2015, 45 (2), 101-114.
Sample preparation for liquid chromatographic analysis of phytochemicals in biological fluids. Phytochem Anal 2014, 25 (4), 314-30.
Decrease in Gastrointestinal Absorption of Roxithromycin in Bile Duct Cannulated Rats due to Depletion of Bile Salts Biopharm Drug Dispos 34(6):360-4.
Menadione serves as a substrate for P-glycoprotein: implication in chemosensitizing activity. Archives of Pharmacal Research 36(4) 509-16. 2013
Simple and sensitive liquid chromatography?tandem mass spectrometry methods for quantification of tadalafil in rat plasma: application to pharmacokinetic study in rats. Archives of Pharmacal Research 36(4), 457-463. 2013
Low-dose probenecid selectively inhibits urinary excretion of phenolsulfonphthalein in rats without affecting biliary excretion. J Appl Toxicol.? 33(6) 511?515. 2013
Pharmacokinetic Interactions of Clopidogrel with Quercetin, Telmisartan, and Cyclosporine A in Rat and Dog. Arch Pharm Res 35(10), 1831-1837, 2012
First-pass metabolism of decursin, a bioactive compound of Angelica gigas, in rats. Planta Medica, 78(9):909-913. 2012
Biliary excretion of curcumin is mediated by multidrug resistance-associated protein 2. Biol Pharmaceut Bull,35(5):777-780. 2012
Effects of Experimental Hyperlipidemia on the Pharmacokinetics of Tadalafil in Rats. J Pharm Pharmaceut Sci 15(4) 528-537. 2012
Comparative pharmacokinetic study of paclitaxel and docetaxel in streptozotocin-induced diabetic rats. Biopharm Drug Dispo,33: 474?486. 2012
The Increased cellular uptake and biliary excretion of curcumin by quercetin: a possible role of albumin binding interaction. Drug Metab. Dispo. 40(8), 1452-1455. 2012
Effects of experimental hyperlipidemia on the pharmacokinetics of docetaxel in rats. Xenobiotica, 41(9), 797-804. 2011
Danshen extract does not alter pharmacokinetics of docetaxel and clopidogrel, reflecting its negligible potential in P-glycoprotein- and cytochrome P4503A-mediated herb-drug interactions. Int J Pharmaceutics, 410(1-2):68-74. 2011
Gas chromatography-mass spectrometry-based simultaneous quantitative analytical method for urinary oxysterols and bile acids in rats. Anal Biochem, 408, 242-252, 2011
Optimization of Experimental Conditions for In vitro P-glycoprotein Assay Using LLC-GA5 Cells. J Pharm Invest, 40(6), 363-366, 2010
Dose-dependent pharmacokinetics of toxic metabolites is not related to increased toxicity following high-dose valproic acid in rats. J Appl Toxicol. 30, 775-8, 2010
Minor effects of citrus flavonoids naringin, naringenin and quercetin, on the pharmacokinetics of doxorubicin in rats. Pharmazie, 66(6):424-9. 2011 Absence of drug interaction between Hwang-Ryun-Hae-Dok-Tang and phenolsulfonphthalein. Arch Pharm Res, 33, 2025-2031, 2010
Discovery of safety biomarkers for atorvastatin in rat urine using mass spectrometry based metabolomics combined with global and targeted approach. Analytica Chimica Acta, 661, 47-59, 2010
Metabolomics Study With Gas Chromatography-Mass Spectrometry for Predicting Valproic Acid-induced Hepatotoxicity and Discovery of Novel Biomarkers in Rat Urine. Int J Toxicol. 28, 392-404. 2009
The relationship between glucuronide conjugate levels and hepatotoxicity after oral administration of valproic acid. Arch Pharm Res. 32, 1029-35. 2009
Biliary clearance of bromosulfophthalein in anesthetized and freely moving conscious rat. Biopharm Drug Dispos. 30, 94-8. 2009
Effect of analytical method on the pharmacokinetic evaluation of bromosulfophthalein: comparison of HPLC and UV spectroscopy method. J Kor Pharm Sci, 38, 399-403, 2008
The antipsychotic sultopride is overdosed--1 PET study of drug-induced receptor occupancy in comparison with sulpiride. Int J Neuropsychopharmacol. 9, 539-545, 2006
Evaluation of in vivo P-glycoprotein function at the blood-brain barrier among MDR1 gene polymorphisma by using 11C-verapamil. J Nucl Med. 47, :1427-1433, 2006
In vivo evaluation of P-glycoprotein function at the blood-brain barrie in nonhuman primates using verapamil. J. Pharmacol Exp. Ther, 316, 647-653, 2006
Lack of contribution of P-gp to transport via the mouse blood-cerebrospinal fluid barrier. J Health Sci, 51, 101-105, 2005
Limited role of P-glycoprotein in the intestinal absorption of Cyclosporin A. Biol Pharm Bull 28, 760-3 2005
Investigation of efflux transport of dehydroepiandrosterone sulfate and mitoxantrone at the mouse blood-brain barrier: a minor role of breast cancer resistance protein. J Pharmacol Exp Ther. 312, 44-52, 2005.
Do Mrp1 and Mrp2 play any role in the elimination of estradiol-17¥â-glucuronide and 2,4-dinitrophenyl-S-glutathione across the blood-cerebrospinal fluid barrier? J. Pharm. Sci, 93, 99-107, 2004.
Deproteinization with ZnSO4?Ba(OH)2 reduces the photodegradation of montelukast during plasma sample preparation for HPLC analysis. J Liq Chromatogr Relat Technol 2016, 39 (11), 520-525.
Designing of the fixed-dose gastroretentive bilayer tablet for sustained release of metformin and immediate release of atorvastatin. Drug Dev Ind Pharm 2016, 42 (2), 340-9.
Relative bioavailability of levodropropizine 60-mg capsule and syrup formulations in healthy male Korean volunteers: a single-dose, randomized-sequence, open-label, two-way crossover study. Int J Clin Pharmcol Ther. 51(2) 152-160. 2013
Determination of Cd bioaccessibility in herbal medicines and safety assessment by in vitro dissolution and ICP-AES. Microchimica Acta 167, 117-122. 2010
A literature survey of the modern techniques used for the processing of herbal medicines. J Kor Pharm Sci, 39, 275-297, 2009
One-step sample size determination for 2x2 Bioequivalence study. J Kor Pharm Sci, 39, 217-219, 2009
The prevention of cyclosporin A adsorption to Transwell surfaces by human plasma Int. J. Pharm. 224, 201-204, 2001
Nasal absorption of procyclidine in rats and dogs Arch. Pharm. Res. 24, 219-223, 2001
The potential replacement of study by 125I-RIA for the characterization of cyclosporin: A bioavailability after oral administration in healthy human subjects J. Pharm. Biomed. Anal., 22, 183-188, 2000
Analysis of bioequivalence study using log-transformed model Yakhakhoeji, 44, 308-314, 2000
Bioequivalency of Neoplanta capsule to Sandimmune Neoral capsule in human subjects Int. J. Clin. Pharmacol. Ther., 36, 210-215, 1998
Statistical analysis of three sequence-three periods bioequivalence study: Application to bioequivalence test of ondansetron formulations J. Kor. Pharm. Sci., 28, 35-42, 1998
Accelerated oral absorption of gliclazide in human subjects from a soft gelatin capsule containing a PEG 400 suspension of gliclazide J. Cont. Rel., 51, 185-192, 1998
Development of K-BEtest, a computer program for the analysis of bioequivalence J. Kor. Pharm. Sci., 28, 223-229, 1998
Decreased oral availability of cyclosporine at second administration in human Br. J. Clin. Pharmacol., 44, 343-345, 1997
Proliposomal clenbuterol patch for transdermal delivery J. Kor. Pharm. Sci., 27, 303-311, 1997
Bioequivalence study of nabumetone tablets in man Arch. Pharm. Res., 18, 340-345, 1995